Imaging Systems

Cancer diagnosis by microscopic axial super-resolving reconstruction approach of cytological and histological images

[+] Author Affiliations
Zeev Zalevsky

Bar-Ilan University, School of Engineering, Ramat-Gan 52900, Israel

Eran Rosmann

Tel-Aviv University, Faculty of Engineering, 69978 Tel-Aviv, Israel

Edmond Sabo

Carmel Medical Center, Department of Pathology, 34362 Haifa, Israel

Ehud Rivlin

Technion—Israel Institute of Technology, Computer Science Deptartment, 3200 Haifa, Israel

David Mendlovic

Tel-Aviv University, Faculty of Engineering, 69978 Tel-Aviv, Israel

Opt. Eng. 45(8), 083201 (September 01, 2006). doi:10.1117/1.2336413
History: Received October 22, 2006; Accepted January 23, 2006; Published September 01, 2006
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We present an optical data reconstruction method to be used for cancer diagnostics via cytological and histological images. The approach allows realizing extended depth of focus and data compression using wavelet transformation that is realized optically with very low computational complexity. The extended depth of focus and the compressed images are generated out of a set of optically defocused images realized due to axial translation of the diagnosed sample. The extended depth of focus image may be used for 3-D cytological information display without stereo projection. Note that the extended depth of focus actually means super-resolving imaging, since getting out of focus means filtering the high band spatial frequencies within the image.

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© 2006 Society of Photo-Optical Instrumentation Engineers

Citation

Zeev Zalevsky ; Eran Rosmann ; Edmond Sabo ; Ehud Rivlin and David Mendlovic
"Cancer diagnosis by microscopic axial super-resolving reconstruction approach of cytological and histological images", Opt. Eng. 45(8), 083201 (September 01, 2006). ; http://dx.doi.org/10.1117/1.2336413


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