Preliminary study of a phase-contrast cone-beam computed tomography system: the edge-enhancement effect in the tomographic reconstruction of in-line holographic images

Weixing Cai; Ruola Ning

doi:10.1117/1.2897284

1 March 2008 Preliminary study of a phase-contrast cone-beam computed tomography system: the edge-enhancement effect in the tomographic reconstruction of in-line holographic images

Weixing Cai, Ruola Ning

Author Affiliations +

Optical Engineering, Vol. 47, Issue 3, 037004 (March 2008). https://doi.org/10.1117/1.2897284

Abstract

A phase-contrast cone-beam computed tomography (PC CBCT) system is proposed for small-animal imaging that incorporates the in-line holography technique into CBCT system. Theoretical analysis shows that the in-line holographic image can be approximately transformed into line integrals of an object function composed of an attenuation term and a phase term. The Fresnel diffraction theory is applied to generate in-line holographic images along a circular orbit, and the Feldkamp-Davis-Kress algorithm is applied to reconstruct the object function. The proposed system was investigated using a numerical phantom, and the reconstruction was evaluated using the edge-enhancement factor and the relative reconstruction error. The reconstruction results show that all the structures in the numerical phantom are bounded with enhanced edges with negligible artifacts. These enhanced edges make the reconstruction visually sharper and clearer. The results show that while the relative reconstruction errors are very close to that of the conventional CBCT reconstruction, having a small cone angle, weak attenuation, small focal spot size, and high-resolution detector are preferred for a greater edge-enhancement effect.

©(2008) Society of Photo-Optical Instrumentation Engineers (SPIE)

Citation Download Citation

Weixing Cai and Ruola Ning "Preliminary study of a phase-contrast cone-beam computed tomography system: the edge-enhancement effect in the tomographic reconstruction of in-line holographic images," Optical Engineering 47(3), 037004 (1 March 2008). https://doi.org/10.1117/1.2897284

Published: 1 March 2008

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available