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Imaging Systems

Real-time reference A-line subtraction and saturation artifact removal using graphics processing unit for high-frame-rate Fourier-domain optical coherence tomography video imaging

[+] Author Affiliations
Yong Huang

The Johns Hopkins University, Department of Electrical and Computer Engineering, Barton Hall 402, 3400 North Charles Street, Baltimore, Maryland 21210

Jin U. Kang

The Johns Hopkins University, Department of Electrical and Computer Engineering, Barton Hall 402, 3400 North Charles Street, Baltimore, Maryland 21210

Opt. Eng. 51(7), 073203 (Jul 06, 2012). doi:10.1117/1.OE.51.7.073203
History: Received March 13, 2012; Revised April 19, 2012; Accepted May 21, 2012
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Abstract.  Variations in the spectral shape and the amplitude of the optical coherence tomography (OCT) signal and reference cause fixed-pattern noise and light reflected from a highly specular surface might cause saturation artifacts. In real-time video-rate OCT imaging, these effects make the OCT video image appear unstable and difficult to view. To eliminate these problems, we implemented real-time reference A-line subtraction and saturation detection and correction on standard Fourier-domain optical coherence tomography (FD-OCT) video imaging frame-by-frame. This real-time OCT data processing method eliminates the need for the physical reference measurement procedure and automatically detects and corrects saturated A-scans if there is any within one frame. This technique is also robust to the reference and signal amplitude variations, and provides higher signal-to-noise ratio compared to the normal fixed-reference subtraction method. To implement an effective interventional OCT imaging system, the technique was integrated along with other graphics processing unit-based OCT processing techniques [resampling, dispersion compensation, fast Fourier transform, log-scaling, and soft-thresholding]. The real-time fixed-pattern artifact-free FD-OCT imaging was achieved at 70frames/s for a frame size of 1000 (lateral) by 1024 (axial) pixels. The theoretical maximum processing and rendering rate was measured to be 266,000A-scans/s.

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© 2012 Society of Photo-Optical Instrumentation Engineers

Citation

Yong Huang and Jin U. Kang
"Real-time reference A-line subtraction and saturation artifact removal using graphics processing unit for high-frame-rate Fourier-domain optical coherence tomography video imaging", Opt. Eng. 51(7), 073203 (Jul 06, 2012). ; http://dx.doi.org/10.1117/1.OE.51.7.073203


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