By cascading two standard Mach–Zehnder modulators (MZMs), we propose and demonstrate a scheme to effectively eliminate the cross-modulation distortion (XMD), which results from the out-of-band interference in multicarrier intensity-modulation direct-detection (IMDD) analog photonic links. When the bias angle of the cascaded modulator is specifically designed, the XMDs, both from the photonic link itself and from the nonlinear electrical amplifiers, are well suppressed. Our proposal is theoretically analyzed, and the performance of the cascading system is experimentally demonstrated. A suppression ratio of more than 30 dB is achieved by the cascading scheme. By using the high-performance pre- and postamplifiers, the measured link gain and noise figure are improved by 62 and 32 dB, respectively.