Highly integrated lab-on-a-chip for fluorescence detection

Surya S.  K. Guduru; Francesco Scotognella; Alessandro Chiasera; Valligatla Sreeramulu; Luigino Criante; Krishna Chaitanya Vishnubhatla; Maurizio Ferrari; Roberta Ramponi; Guglielmo Lanzani; Rebeca Martínez Vázquez

doi:10.1117/1.OE.55.9.097102

2 September 2016 Highly integrated lab-on-a-chip for fluorescence detection

Surya S. K. Guduru, Francesco Scotognella, Alessandro Chiasera, Valligatla Sreeramulu, Luigino Criante, Krishna Chaitanya Vishnubhatla, Maurizio Ferrari, Roberta Ramponi, Guglielmo Lanzani, Rebeca Martínez Vázquez

Author Affiliations +

Optical Engineering, Vol. 55, Issue 9, 097102 (September 2016). https://doi.org/10.1117/1.OE.55.9.097102

Abstract

We report the fabrication and validation of a microfluidic chip for fluorescence detection, which incorporates in the same glass substrate the microfluidic network, the excitation, the filtering, and the collection elements. The device is fabricated in a hybrid approach combining different technologies, such as femtosecond laser micromachining and RF sputtering, to increase their individual capabilities. The validation of the chip demonstrates a good wavelength selective light filtering and a limit of detection of a 600-nM concentration of Oxazine 720 perchlorate dye.

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Surya S. K. Guduru, Francesco Scotognella, Alessandro Chiasera, Valligatla Sreeramulu, Luigino Criante, Krishna Chaitanya Vishnubhatla, Maurizio Ferrari, Roberta Ramponi, Guglielmo Lanzani, and Rebeca Martínez Vázquez "Highly integrated lab-on-a-chip for fluorescence detection," Optical Engineering 55(9), 097102 (2 September 2016). https://doi.org/10.1117/1.OE.55.9.097102

Published: 2 September 2016

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