Imaging Components, Systems, and Processing

Bayesian reconstruction of quantitative photoacoustic tomography considering modeling error of the optical diffusion equation

[+] Author Affiliations
Hui Zhang, Si Chen, Wei Zou, Danfeng Hu, Jiajun Wang

Soochow University, School of Electronic and Information Engineering, No. 1 ShiZhi Street, Suzhou 215006, Jiangsu Province, China

Xin Gao

Chinese Academy of Science, Suzhou Institute of Biomedical Engineering and Technology, Suzhou 215163, China

Opt. Eng. 55(9), 093101 (Sep 06, 2016). doi:10.1117/1.OE.55.9.093101
History: Received February 24, 2016; Accepted August 16, 2016
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Abstract.  In the reconstruction of the quantitative photoacoustic tomography (QPAT), forward models for both the optical and acoustic problems are usually needed to predict the measurement data from a guess of the distribution of the optical parameters. The diffusion approximation (DA) is the one most often employed as the optical forward model in the QPAT. However, this model usually results in predicted data deviating far from the actual measurements especially in low scattering tissues. To tackle such a problem, we propose a reconstruction method where the modeling error of the DA is modeled and considered in the framework of Bayesian inference. Experimental results show that modeling of the approximation error and considering it in the reconstruction procedure can significantly improve the reconstructed results of the QPAT.

© 2016 Society of Photo-Optical Instrumentation Engineers

Citation

Hui Zhang ; Si Chen ; Wei Zou ; Danfeng Hu ; Xin Gao, et al.
"Bayesian reconstruction of quantitative photoacoustic tomography considering modeling error of the optical diffusion equation", Opt. Eng. 55(9), 093101 (Sep 06, 2016). ; http://dx.doi.org/10.1117/1.OE.55.9.093101


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