A novel paper-based substrate for coffee ring augmented surface-enhanced Raman spectroscopy

Anna S. Rourke; Alec Walter; Braden Carroll; Anita Mahadevan-Jansen; Andrea Locke

doi:10.1117/12.2609871

12 May 2022 A novel paper-based substrate for coffee ring augmented surface-enhanced Raman spectroscopy

Anna S. Rourke, Alec Walter, Braden Carroll, Anita Mahadevan-Jansen, Andrea Locke

Proceedings Volume PC11968, Optical Diagnostics and Sensing XXII: Toward Point-of-Care Diagnostics; PC1196802 (2022) https://doi.org/10.1117/12.2609871
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Coupling of surface-enhanced Raman spectroscopy (SERS) with the coffee ring effect can overcome the poor reproducibility typically seen when using SERS. In this study, we developed a nitrocellulose membrane paper-based substrate for coffee ring enhanced SERS, which was highly hydrophobic and produced consistent coffee rings. After optimization of solution parameters including gold nanoparticle concentration and solvent, this platform demonstrated high enhancement and low variability using Malachite Green Isothiocyanate and Moraxella catarrhalis. This substrate has the potential to increase the usability and implementation of SERS by overcoming intrinsic limitations and is more accessible than current substrates.

Conference Presentation

Citation Download Citation

Anna S. Rourke, Alec Walter, Braden Carroll, Anita Mahadevan-Jansen, and Andrea Locke "A novel paper-based substrate for coffee ring augmented surface-enhanced Raman spectroscopy", Proc. SPIE PC11968, Optical Diagnostics and Sensing XXII: Toward Point-of-Care Diagnostics, PC1196802 (12 May 2022); https://doi.org/10.1117/12.2609871

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