Wide field-of-view high lateral resolution optical coherence tomography with 3D image stitching and superresolution

Kai Shen; Sarfaraz Baig; Guomin Jiang; Michael R. Wang

doi:10.1117/12.2287480

14 February 2018 Wide field-of-view high lateral resolution optical coherence tomography with 3D image stitching and superresolution

Kai Shen, Sarfaraz Baig, Guomin Jiang, Michael R. Wang

Author Affiliations +

Proceedings Volume 10483, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXII; 104832R (2018) https://doi.org/10.1117/12.2287480
Event: SPIE BiOS, 2018, San Francisco, California, United States

Abstract

We report that wide field-of-view (FOV) optical coherence tomography images with high lateral resolution can be obtained by using superresolution and 3D image stitching techniques. About 3 times lateral resolution improvement from 6.20 μm to 2.19 μm using a focusing lens of 0.08 numerical aperture has been demonstrated. With such lens the FOV is generally small owing to off-axis focusing degradation. To enlarge the FOV while maintaining high lateral resolution, 3D image stitching technique is introduced to effectively reconstruct an ultra-wide FOV 3D image of 2.10x1.15 mm² lateral area from ten C-scans of 500×500 μm² FOV. Improved FOV with high lateral resolution should benefit various biomedical imaging applications.

Citation Download Citation

Kai Shen, Sarfaraz Baig, Guomin Jiang, and Michael R. Wang "Wide field-of-view high lateral resolution optical coherence tomography with 3D image stitching and superresolution", Proc. SPIE 10483, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXII, 104832R (14 February 2018); https://doi.org/10.1117/12.2287480

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