Modeling diffuse reflectance spectra of donated blood with their hematological parameters

Osman Melih Can; Yekta Ülgen

doi:10.1117/12.2526848

11 July 2019 Modeling diffuse reflectance spectra of donated blood with their hematological parameters

Osman Melih Can, Yekta Ülgen

Proceedings Volume 11074, Diffuse Optical Spectroscopy and Imaging VII; 110741T (2019) https://doi.org/10.1117/12.2526848
Event: European Conferences on Biomedical Optics, 2019, Munich, Germany

Abstract

Diffuse reflectance spectroscopy was successfully applied in transfusion medicine, for the diagnosis of the quality of blood units, in recent studies. However, removal of blood sample from the bag is still required for measuring donor dependent hematological variations in stored units. If these hematological variables are successfully interpreted from diffuse reflectance spectra, there would be no need for invasive tests. In this study, diffuse reflectance spectra of 103 erythrocyte suspensions were modeled with their donor-dependent hematological variations on the first day of storage. The final model given in this study, fitted well at 610 nm with goodness of fit of 0.94 for erythrocyte suspensions and 0.96 for 87 leukocyte-depleted units, when selecting 474 nm for normalizing diffuse reflectance spectra of each blood unit and minimizing the effects of plastic blood bag.

Citation Download Citation

Osman Melih Can and Yekta Ülgen "Modeling diffuse reflectance spectra of donated blood with their hematological parameters", Proc. SPIE 11074, Diffuse Optical Spectroscopy and Imaging VII, 110741T (11 July 2019); https://doi.org/10.1117/12.2526848

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available