Acetylcholinesterase-based biosensing solutions for the detection of organophosphorus pesticides

Piotr Walter; Andrzej Pepłowski; Daniel Janczak; Małgorzata Jakubowska

doi:10.1117/12.2536965

6 November 2019 Acetylcholinesterase-based biosensing solutions for the detection of organophosphorus pesticides

Piotr Walter, Andrzej Pepłowski, Daniel Janczak, Małgorzata Jakubowska

Proceedings Volume 11176, Photonics Applications in Astronomy, Communications, Industry, and High-Energy Physics Experiments 2019; 111762V (2019) https://doi.org/10.1117/12.2536965
Event: Photonics Applications in Astronomy, Communications, Industry, and High-Energy Physics Experiments 2019, 2019, Wilga, Poland

Abstract

Numerous biosensing configurations have been researched for detection of organophosphorus pesticides in agricultural and household applications. Selectivity for the specific insecticide, sensitivity and low detection limit being the main challenges gives a great potential to targeted enzymatic biosensors. Acetylcholinesterase is being employed in receptors, because organophosphorus pesticides, such as malathion, display inhibitory effect towards it. Proteins within other structures can have decreased activity, be contaminated, denatured or have a diffusion barrier resulting in reduced interaction with the analyte. Choice of the immobilization method for the enzyme may be the most important aspect in the development of electrochemical biosensor. Numerous acetylcholinesterase based biosensing solutions for the detection of organophosphorus pesticides have been reviewed.

Citation Download Citation

Piotr Walter, Andrzej Pepłowski, Daniel Janczak, and Małgorzata Jakubowska "Acetylcholinesterase-based biosensing solutions for the detection of organophosphorus pesticides", Proc. SPIE 11176, Photonics Applications in Astronomy, Communications, Industry, and High-Energy Physics Experiments 2019, 111762V (6 November 2019); https://doi.org/10.1117/12.2536965

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