5 March 2021Measurement and uniformization of power distribution on the prism for biomedical applications of mid-infrared, attenuated-total-reflection spectroscopy
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To obtain uniform power distribution on the ATR prism for biomedical spectroscopy system, the power intensity mapping on the prism is precisely measured by using a newly developed probing technique. It is found that the distribution of QCL based system is less uniform than that of the FT-IR based system due to the high coherency of the laser beam. To homogenize the distribution, a lens is introduced to diffuse the light and the incident beam is inclined to increase the number of reflections in the prism. As a result, we confirmed that the measurement error of in-vivo experiments is suppressed.
T. Koyama,S. Kino,T. Sasaki,Y. Wada,R. Kasahara,Y. Oba, andY. Matsuura
"Measurement and uniformization of power distribution on the prism for biomedical applications of mid-infrared, attenuated-total-reflection spectroscopy", Proc. SPIE 11635, Optical Fibers and Sensors for Medical Diagnostics, Treatment and Environmental Applications XXI, 116350O (5 March 2021); https://doi.org/10.1117/12.2582270
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T. Koyama, S. Kino, T. Sasaki, Y. Wada, R. Kasahara, Y. Oba, Y. Matsuura, "Measurement and uniformization of power distribution on the prism for biomedical applications of mid-infrared, attenuated-total-reflection spectroscopy," Proc. SPIE 11635, Optical Fibers and Sensors for Medical Diagnostics, Treatment and Environmental Applications XXI, 116350O (5 March 2021); https://doi.org/10.1117/12.2582270