Changes in optical density of vascular tissue after 308-nm excimer laser irradiation

Hans-Joachim Schwarzmaier M.D.; Matthias P. Heintzen; Wolfram Mueller; Raimund Kaufmann; Myron Lee Wolbarsht

doi:10.1117/12.137295

28 August 1992 Changes in optical density of vascular tissue after 308-nm excimer laser irradiation

Hans-Joachim Schwarzmaier M.D., Matthias P. Heintzen, Wolfram Mueller, Raimund Kaufmann, Myron Lee Wolbarsht

Proceedings Volume 1642, Diagnostic and Therapeutic Cardiovascular Interventions II; (1992) https://doi.org/10.1117/12.137295
Event: OE/LASE '92, 1992, Los Angeles, CA, United States

Abstract

Ninety-six transmission spectra were obtained from autopsy specimens of healthy human abdominal aorta. Specimens were irradiated via a 900 micrometers fused silica fiber (contact mode) under normal saline at room temperature (21.5 +/- 1.5 degree(s)C) using an excimer laser (308 nm, 40 Hz, 115 ns, 57 mJ/mm²). The temperature increased at the fiber tip up to 66.8 +/- 8.5 degree(s)C and was monitored by a NiCrNi thermocouple. Tissue samples from untreated areas and from the thermal damage zone next to the ablation area were anayzed by microspectrophotometry (spectral range 250-800 nm, cryosections 24 micrometers , area measured 6/3 (mu) in diameter). The conclusion is, excimer laser irradiation using a high repetition rate in combination with a high output energy changes the optical properties of human vessel walls significantly.

Citation Download Citation

Hans-Joachim Schwarzmaier M.D., Matthias P. Heintzen, Wolfram Mueller, Raimund Kaufmann, and Myron Lee Wolbarsht "Changes in optical density of vascular tissue after 308-nm excimer laser irradiation", Proc. SPIE 1642, Diagnostic and Therapeutic Cardiovascular Interventions II, (28 August 1992); https://doi.org/10.1117/12.137295

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
7 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Absorbance

Tissue optics

Excimer lasers

Laser tissue interaction

Laser irradiation

Optical properties

Tissues

Show All Keywords

Keywords/Phrases

Search In:

Publication Years