Ultrasensitive intracavity molecular spectroscopy for diagnostic applications

Eugeni P. Gordov; Michail M. Makogon; Iren V. Sukhodolo

doi:10.1117/12.180797

21 July 1994 Ultrasensitive intracavity molecular spectroscopy for diagnostic applications

Eugeni P. Gordov, Michail M. Makogon, Iren V. Sukhodolo

Proceedings Volume 2136, Biochemical Diagnostic Instrumentation; (1994) https://doi.org/10.1117/12.180797
Event: OE/LASE '94, 1994, Los Angeles, CA, United States

Abstract

Intracavity laser spectroscopy (ILS) presents itself as a highly effective technique that allows one to detect the change of light signal from absorbing molecules at a level of radiation quantum noise. Thus high sensitivity of ICLS allows one to determine the absorbing molecules concentrations in gases and liquids in the range between 10^-6 to 10^-10. The potential of ICLS technique employment for establishing interrelations between small changes in the breathed air caused by diseases in the early stage, as well as a mass screening of patients with diseases of the liver and kidneys by acetone and urea detection in breathed air, and with heart diseases by measurement of CO₂ concentration is discussed. Usage of gas, dye and solid-state lasers for such measurements is analyzed, optimum spectral ranges are presented.

Citation Download Citation

Eugeni P. Gordov, Michail M. Makogon, and Iren V. Sukhodolo "Ultrasensitive intracavity molecular spectroscopy for diagnostic applications", Proc. SPIE 2136, Biochemical Diagnostic Instrumentation, (21 July 1994); https://doi.org/10.1117/12.180797

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