Modeling the optical coherence tomography geometry using the extended Huygens-Fresnel principle and Monte Carlo simulations

Peter E. Andersen; Lars Thrane; Harold T. Yura; Andreas Tycho; Thomas Martini Joergensen

doi:10.1117/12.388064

13 June 2000 Modeling the optical coherence tomography geometry using the extended Huygens-Fresnel principle and Monte Carlo simulations

Peter E. Andersen, Lars Thrane, Harold T. Yura, Andreas Tycho, Thomas Martini Joergensen

Author Affiliations +

Proceedings Volume 3914, Laser-Tissue Interaction XI: Photochemical, Photothermal, and Photomechanical; (2000) https://doi.org/10.1117/12.388064
Event: BiOS 2000 The International Symposium on Biomedical Optics, 2000, San Jose, CA, United States

Abstract

We have developed a new theoretical description of the optical coherence tomography (OCT) geometry for imaging in highly scattering tissue. The new model is based on the extended Huygens-Fresnel principle, and it is valid in the single and multiple scattering regimes. The so-called shower curtain effect, which manifests itself in standard OCT systems, is an inherent property of the extended Huygens-Fresnel model. We compare the theoretical analysis with experiments carried out on samples consisting of aqueous suspensions of microspheres and solid phantoms. We calculate the signal-to-noise ratio, and provide an estimation of the maximum attainable probing depth for shot-noise limited detection. Furthermore, we investigate the focusing of the Gaussian probe beam in the tissue using Monte Carlo simulations, and compare it to the extended Huygens-Fresnel model. Finally, we simulate the operation of the OCT system using a specially adapted Monte Carlo simulation code.

Citation Download Citation

Peter E. Andersen, Lars Thrane, Harold T. Yura, Andreas Tycho, and Thomas Martini Joergensen "Modeling the optical coherence tomography geometry using the extended Huygens-Fresnel principle and Monte Carlo simulations", Proc. SPIE 3914, Laser-Tissue Interaction XI: Photochemical, Photothermal, and Photomechanical, (13 June 2000); https://doi.org/10.1117/12.388064

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