Sonoluminescence optical confocal scanning tomography of tissue

Yonghong He; Da Xing

doi:10.1117/12.429314

15 June 2001 Sonoluminescence optical confocal scanning tomography of tissue

Yonghong He, Da Xing

Proceedings Volume 4256, Biomedical Optoacoustics II; (2001) https://doi.org/10.1117/12.429314
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States

Abstract

In this paper, we first report experiments on confocal tomography of sonoluminescence media with objects buried in both biological tissue and tissue-simulating media. A high-sensitive confocal scanning setup based on photon counting technique was developed. With the system, a carbon cube buried in tissue simulation medium was imaged with high contrast and a lateral resolution of about 100μm. For the tissue experiment a carbon stick buried in muscle tissue was optically sectioned with the sonoluminescence confocal scanning technique. The spatial resolution of the image at present is limited by the intensity of the sonoluminescence, and could be largely improved by increasing the intensity of emission by a sono-chemluminescence method. The optical tomography of sono-chemluminescence method has potential applications in clinical diagnosis.

Citation Download Citation

Yonghong He and Da Xing "Sonoluminescence optical confocal scanning tomography of tissue", Proc. SPIE 4256, Biomedical Optoacoustics II, (15 June 2001); https://doi.org/10.1117/12.429314

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