Use of tethering for axial confinement in optical tweezers

Mark Cronin-Golomb

doi:10.1117/12.558203

18 October 2004 Use of tethering for axial confinement in optical tweezers

Mark Cronin-Golomb

Proceedings Volume 5514, Optical Trapping and Optical Micromanipulation; (2004) https://doi.org/10.1117/12.558203
Event: Optical Science and Technology, the SPIE 49th Annual Meeting, 2004, Denver, Colorado, United States

Abstract

Lambda DNA is used to tether polystyrene microspheres to an optical substrate, thus eliminating the need for high numerical aperture trapping lenses in single beam optical tweezers to provide axial trapping. The tethered particle may be used as a sensor probe to measure local viscosity and forces on the trapped particle such as those induced by fluid flow.

Citation Download Citation

Mark Cronin-Golomb "Use of tethering for axial confinement in optical tweezers", Proc. SPIE 5514, Optical Trapping and Optical Micromanipulation, (18 October 2004); https://doi.org/10.1117/12.558203

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