A study on a portable fluorescence imaging system

Han-Chao Chang; Wen-Hong Wu; Chun-Li Chang; Kuo-Cheng Huang; Chung-Hsing Chang; Shang-Chen Chiu

doi:10.1117/12.892297

24 September 2011 A study on a portable fluorescence imaging system

Han-Chao Chang, Wen-Hong Wu, Chun-Li Chang, Kuo-Cheng Huang, Chung-Hsing Chang, Shang-Chen Chiu

Proceedings Volume 8135, Applications of Digital Image Processing XXXIV; 81351Z (2011) https://doi.org/10.1117/12.892297
Event: SPIE Optical Engineering + Applications, 2011, San Diego, California, United States

Abstract

The fluorescent reaction is that an organism or dye, excited by UV light (200-405 nm), emits a specific frequency of light; the light is usually a visible or near infrared light (405-900 nm). During the UV light irradiation, the photosensitive agent will be induced to start the photochemical reaction. In addition, the fluorescence image can be used for fluorescence diagnosis and then photodynamic therapy can be given to dental diseases and skin cancer, which has become a useful tool to provide scientific evidence in many biomedical researches. However, most of the methods on acquiring fluorescence biology traces are still stay in primitive stage, catching by naked eyes and researcher's subjective judgment. This article presents a portable camera to obtain the fluorescence image and to make up a deficit from observer competence and subjective judgment. Furthermore, the portable camera offers the 375nm UV-LED exciting light source for user to record fluorescence image and makes the recorded image become persuasive scientific evidence. In addition, when the raising the rate between signal and noise, the signal processing module will not only amplify the fluorescence signal up to 70 %, but also decrease the noise significantly from environmental light on bill and nude mouse testing.

Citation Download Citation

Han-Chao Chang, Wen-Hong Wu, Chun-Li Chang, Kuo-Cheng Huang, Chung-Hsing Chang, and Shang-Chen Chiu "A study on a portable fluorescence imaging system", Proc. SPIE 8135, Applications of Digital Image Processing XXXIV, 81351Z (24 September 2011); https://doi.org/10.1117/12.892297

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
6 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Luminescence

Signal processing

Ultraviolet radiation

Cameras

Interference (communication)

Digital cameras

Imaging systems

Show All Keywords

Keywords/Phrases

Search In:

Publication Years