Automated localization of wrinkles and the dermo-epidermal junction in obliquely oriented reflectance confocal microscopic images of human skin

Jamshid Sourati; Kivanc Kose; Milind Rajadhyaksha; Jennifer G. Dy; Deniz Erdogmus; Dana H. Brooks

doi:10.1117/12.2006489

22 February 2013 Automated localization of wrinkles and the dermo-epidermal junction in obliquely oriented reflectance confocal microscopic images of human skin

Jamshid Sourati, Kivanc Kose, Milind Rajadhyaksha, Jennifer G. Dy, Deniz Erdogmus, Dana H. Brooks

Author Affiliations +

Proceedings Volume 8565, Photonic Therapeutics and Diagnostics IX; 856503 (2013) https://doi.org/10.1117/12.2006489
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

Reflectance Confocal Microscopic (RCM) imaging of obliquely-oriented optical sections, rather than with traditional z-stacks, shows depth information that more closely mimics the appearance of skin in orthogonal sections of histology. This approach may considerably reduce the amount of data that must be acquired and processed. However, as with z-stacks, purely visual detection of the dermal-epidermal junction (DEJ) in oblique images remains challenging. Here, we have extended our original algorithm for localization of DEJ in z-stacks to oblique images. In addition, we developed an algorithm for detecting wrinkles, which in addition to its intrinsic merit, gives useful information for DEJ detection.

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Jamshid Sourati, Kivanc Kose, Milind Rajadhyaksha, Jennifer G. Dy, Deniz Erdogmus, and Dana H. Brooks "Automated localization of wrinkles and the dermo-epidermal junction in obliquely oriented reflectance confocal microscopic images of human skin", Proc. SPIE 8565, Photonic Therapeutics and Diagnostics IX, 856503 (22 February 2013); https://doi.org/10.1117/12.2006489

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