Dynamic speckle interferometry of microscopic processes in solid state and thin biological objects

A. P. Vladimirov

doi:10.1117/12.2196100

24 August 2015 Dynamic speckle interferometry of microscopic processes in solid state and thin biological objects

A. P. Vladimirov

Proceedings Volume 9660, SPECKLE 2015: VI International Conference on Speckle Metrology; 966017 (2015) https://doi.org/10.1117/12.2196100
Event: SPECKLE 2015: VI International Conference on Speckle Metrology, 2015, Guanajuato, Mexico

Abstract

Modernized theory of dynamic speckle interferometry is considered. It is shown that the time-average radiation intensity has the parameters characterizing the wave phase changes. It also brings forward an expression for time autocorrelation function of the radiation intensity. It is shown that with the vanishing averaging time value the formulas transform to the prior expressions. The results of experiments with high-cycle material fatigue and cell metabolism analysis conducted using the time-averaging technique are discussed. Good reproducibility of the results is demonstrated. It is specified that the upgraded technique allows analyzing accumulation of fatigue damage, detecting the crack start moment and determining its growth velocity with uninterrupted cyclic load. It is also demonstrated that in the experiments with a cell monolayer the technique allows studying metabolism change both in an individual cell and in a group of cells.

Citation Download Citation

A. P. Vladimirov "Dynamic speckle interferometry of microscopic processes in solid state and thin biological objects", Proc. SPIE 9660, SPECKLE 2015: VI International Conference on Speckle Metrology, 966017 (24 August 2015); https://doi.org/10.1117/12.2196100

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