A wearable optical device for continuous monitoring during neoadjuvant chemotherapy infusions

Fei Teng; Timothy Cormier; Alexis Sauer-Budge; Darren M. Roblyer

doi:10.1117/12.2208438

4 March 2016 A wearable optical device for continuous monitoring during neoadjuvant chemotherapy infusions

Fei Teng, Timothy Cormier, Alexis Sauer-Budge, Darren M. Roblyer

Proceedings Volume 9715, Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics; 97150P (2016) https://doi.org/10.1117/12.2208438
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

We present a new continuous-wave (CW) wearable diffuse optical device aimed at investigating the hemodynamic response of locally advanced breast cancer patients during a patient’s first neoadjuvant chemotherapy infusion. The system consists of a flexible substrate that supports an array of surface-mount LED and photodiode pairs (i.e. optodes). Probe performance was evaluated using solid tissue-simulating phantoms. Measurements revealed high SNR (65dB), low source-detector crosstalk (-59 dB), high measurement precision (0.17%), and good thermal stability (0.2% V_rms/°C). A cuff occlusion experiment was performed on the forearm of a healthy volunteer to demonstrate the ability to track rapid hemodynamic changes.

Conference Presentation

Citation Download Citation

Fei Teng, Timothy Cormier, Alexis Sauer-Budge, and Darren M. Roblyer "A wearable optical device for continuous monitoring during neoadjuvant chemotherapy infusions", Proc. SPIE 9715, Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics, 97150P (4 March 2016); https://doi.org/10.1117/12.2208438

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available