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6 March 2023 Development of a glass-based imaging phantom to model the optical properties of human tissue
Mingze Yang, Yunle Wei, Philipp Reineck, Heike Ebendorff-Heidepriem, Jiawen Li, Robert A McLaughlin
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Proceedings Volume PC12370, Design and Quality for Biomedical Technologies XVI; PC1237001 (2023) https://doi.org/10.1117/12.2647470
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
The fabrication of a stable, reproducible optical imaging phantom is critical to the assessment and optimization of optical imaging systems. In this study, we present a novel design of optical phantom based on metal-doped glass-ceramics. The matrix was doped with nickel ions to imitate the absorption of haemoglobin, and scattering levels representative of tissue were induced through controlled crystallisation in the glass-based phantom at elevated temperature. Our glass-based optical phantom can provide controlled levels of optical scattering and absorption to mimic the optical properties of human tissues with excellent optical homogeneity, and potentially long-term stability and reproducibility.
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Mingze Yang, Yunle Wei, Philipp Reineck, Heike Ebendorff-Heidepriem, Jiawen Li, and Robert A McLaughlin "Development of a glass-based imaging phantom to model the optical properties of human tissue", Proc. SPIE PC12370, Design and Quality for Biomedical Technologies XVI, PC1237001 (6 March 2023); https://doi.org/10.1117/12.2647470
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KEYWORDS
Tissue optics
Absorption
Optical properties
Scattering
Glasses
Ions
Nickel
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