Multi-channel, long-wavelength, interferometric diffuse correlation spectroscopy for functional perfusion imaging

Mitchell B. Robinson; Kevin Mai; Yoonho Oh; Maria Angela Franceschini; Stefan A. Carp

doi:10.1117/12.3003364

13 March 2024 Multi-channel, long-wavelength, interferometric diffuse correlation spectroscopy for functional perfusion imaging

Mitchell B. Robinson, Kevin Mai, Yoonho Oh, Maria Angela Franceschini, Stefan A. Carp

Author Affiliations +

Proceedings Volume PC12828, Neural Imaging and Sensing 2024; PC128280M (2024) https://doi.org/10.1117/12.3003364
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Interferometric diffuse correlation spectroscopy (iDCS) is an emerging technique that enables high quality measurements of cerebral blood flow. By including a reference arm in the optical setup, the SNR of the measured signals are improved relative to traditional DCS. We report here an expansion of our previously demonstrated 1064 nm single channel line scan camera based iDCS system to a multi-source, multiple detection channel approach to enable imaging of the brain perfusion response to functional activation. We confirm the ability to image multiple detectors on a single camera with minimal cross-talk using phantom experiments and show initial functional imaging results.

Conference Presentation

Citation Download Citation

Mitchell B. Robinson, Kevin Mai, Yoonho Oh, Maria Angela Franceschini, and Stefan A. Carp "Multi-channel, long-wavelength, interferometric diffuse correlation spectroscopy for functional perfusion imaging", Proc. SPIE PC12828, Neural Imaging and Sensing 2024, PC128280M (13 March 2024); https://doi.org/10.1117/12.3003364

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