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13 March 2024 Depth-enhanced diffuse correlation spectroscopy enabled by coherent gain
Mitchell B. Robinson, Marco Renna, Stefan A. Carp, Maria Angela Franceschini
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Proceedings Volume PC12841, Dynamics and Fluctuations in Biomedical Photonics XXI; PC128410C (2024) https://doi.org/10.1117/12.3003352
Event: SPIE BiOS, 2024, San Francisco, California, United States
Abstract
Diffuse correlation spectroscopy (DCS) is an optical technique which is used to estimate blood flow in tissue through the analysis of the temporal fluctuations in light intensity. Recently, the development of interferometric techniques (iDCS/iDWS), have allowed for drastic improvement in measurement SNR. In this work, we build upon the iDCS technique by combining it with another advanced DCS modality, time-domain DCS (TD-DCS). This combination allows for the application of pathlength specific coherent gain, which has the potential to further improve the performance of DCS in the non-invasive measurement of deep tissue blood flow.
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Mitchell B. Robinson, Marco Renna, Stefan A. Carp, and Maria Angela Franceschini "Depth-enhanced diffuse correlation spectroscopy enabled by coherent gain", Proc. SPIE PC12841, Dynamics and Fluctuations in Biomedical Photonics XXI, PC128410C (13 March 2024); https://doi.org/10.1117/12.3003352
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KEYWORDS
Blood circulation
Spectroscopy
Laser sources
Signal detection
Tissues
Laser interferometry
Photons
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