Tissue optics, light distribution, and spectroscopy

Valery V. Tuchin; Sergei R. Utz M.D.; Ilya V. Yaroslavsky

doi:10.1117/12.178900

1 October 1994 Tissue optics, light distribution, and spectroscopy

Valery V. Tuchin, Sergei R. Utz M.D., Ilya V. Yaroslavsky

Author Affiliations +

Optical Engineering, Vol. 33, Issue 10, (October 1994). https://doi.org/10.1117/12.178900

Abstract

A model of multilayered tissue is considered. The Monte Carlo simulation technique is used to study laser beam transport through tissues with varying optical properties for each layer (absorption, scattering, scattering anisotropy factor, and refractive index). Calculations are performed for some models of the human skin and adjacent tissues for visible and UV wavelength ranges. New technology for human epidermis optical parameters determination is presented. This technology includes epidermis upper layers glue stripping; in vitro measurements of total transmission, diffuse reflection, and angular scattering of stripping samples; and using an inverse calculation technique based on four-flux approximation of radiation transport theory. The technology was successfully used for depth dependence monitoring of epidermis optical parameters. An inverse Monte Carlo technique for determining the optical properties of tissues based on spectrophotometric measurements is developed. This technique takes into account the 2-D geometry of the experiment, finite sizes of incident beam and integrating sphere ports, boundary conditions, and sideways losses of light.

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Valery V. Tuchin, Sergei R. Utz M.D., and Ilya V. Yaroslavsky "Tissue optics, light distribution, and spectroscopy," Optical Engineering 33(10), (1 October 1994). https://doi.org/10.1117/12.178900

Published: 1 October 1994

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