In large-scale imaging or measurement, a rotating photogrammetric system with a camera fixed on the surface of the turntable can be used to extend the field of view of the camera with the rotation of the turntable. The camera’s projection center needs to be located at the rotation axis of the turntable, so the images captured during the sequentially rotating share the same projection center. It is very convenient to merge the subimages into a panoramic image. Due to the complexity of the camera’s lens system, the position of the projection center is usually unknown, which makes it difficult to find the projection center and align it with the rotation axis of the turntable. We propose a method to find the distance and azimuth angle between the projection center and rotation axis to solve the alignment problem using the parameters of the camera. In theory, as long as the intrinsic and extrinsic parameters of the camera are known, the distance and angle can be obtained by rotating the turntable once. With the translation values calculated from the distance and angle, the camera can be moved in two directions perpendicular to each other, so its projection center passes through the rotation axis. The theoretical analysis of the alignment problem is given. Experiments verify the feasibility of the proposed method are conducted. The alignment uncertainty of the proposed method is <0.2  mm.