Dr. Pietro Strobbia Profile

Dr. Pietro Strobbia

Assistant Professor at Univ of Cincinnati

SPIE Involvement:

Conference Program Committee | Author

Websites:

Personal Website

Publications (22)

Proceedings Article | 14 June 2023 Paper

Online characterization of bacteria culture using Raman and SERS

Jonathan Pahren, Der Vang, Justin Caserta, Pietro Strobbia, Tom Cambron

Proceedings Volume 12548, 125480E (2023) https://doi.org/10.1117/12.2678153

KEYWORDS: Raman spectroscopy, Bacteria, Surface enhanced Raman spectroscopy, Chemical analysis, Biological research, Proteins, Data modeling

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Hygiene is becoming a key issue in a world with an increasing global population and an increasing number of antibioticresistant bacteria. In the next few years, a crucial challenge will be finding better methods for disinfection. Currently, these methods are studied with traditional microbiology techniques, where bacteria are grown, exposed to a treatment and further growth is followed for several days. However, this paradigm is slow and does not offer chemical insights in the mechanism of action of disinfecting agents. Without new analytical tools, we risk slowing down the critical research into new disinfecting agents. There is a large body of literature reporting bacterial inhibition mechanisms are diverse and include cell membrane disruption, DNA/RNA damage, ribosome degradation, protein denaturation, etc. Also, it is widely known that bacteria inactivation mechanisms are complex and multiple mechanisms can be involved in a synergetic manner. Current knowledge regarding the mechanism of action for bacteria inhibition is largely based on results from analytical tools that include mass spectrometry, nuclear magnetic resonance spectroscopy and fluorescence spectroscopy in combination with a suite of biochemical assays. All these methods require significant effort and sample preparation/treatment to obtain results. In addition, chemical insights obtained from biochemical assays rely tightly to the initial hypotheses. Herein, we propose to use Raman and surface-enhanced Raman scattering (SERS) to study the mechanism of action for bacteria inhibition. Vibrational spectroscopies have numerous advantages over the current paradigm for this analysis, including low sample preparation requirements and spectra rich in chemical information. These advantages permit to monitor bacteria cultures easily and quickly, while also obtaining chemical insights regarding mechanism of action for bacteria inhibition. In this work, we will show the monitoring of treated bacteria via Raman spectroscopy and how we can use SERS to further streamline this process.

Proceedings Article | 3 March 2022 Poster + Paper

In vivo SERS monitoring in plants using plasmonic nanoprobes

Vanessa Cupil-Garcia, Joy Li, Ren Odion, Pietro Strobbia, Bridget Crawford, Hsin-neng Wang, Jianhong Hu, Rodolfo Zentella, Kenneth Kemner, Tai-ping Sun, Tuan Vo-Dinh

Proceedings Volume 11978, 119780B (2022) https://doi.org/10.1117/12.2617364

KEYWORDS: Raman spectroscopy, Nanoprobes, Surface enhanced Raman spectroscopy, In vivo imaging, Gold, Plasmonics, Nanoparticles, Biofuels, Transmission electron microscopy

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Proceedings Article | 12 March 2021 Presentation + Paper

Translation of SERS sensing to real-world settings through the combination with shifted-excitation Raman difference spectroscopy (SERDS)

Pietro Strobbia, Vanessa Cupil-Garcia, Ren Odion, Bridget Crawford, Hsin-Neng Wang, Yang Liu, Martin Maiwald, Bernd Sumpf, Tuan Vo-Dinh

Proceedings Volume 11661, 1166103 (2021) https://doi.org/10.1117/12.2583914

KEYWORDS: Raman spectroscopy, Surface enhanced Raman spectroscopy, Spectroscopy, Tumors, Sensors, Laser development, In vivo imaging, Raman scattering, Nanoprobes

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Proceedings Article | 21 February 2020 Paper

Applications of plasmonic nanoparticles for in vivo biosensing of plants

Vanessa Cupil-Garcia, Pietro Strobbia, Bridget Crawford, Hsin-neng Wang, Rodolfo Zentella, Tai-Ping Sun, Tuan Vo-Dinh

Proceedings Volume 11257, 1125715 (2020) https://doi.org/10.1117/12.2553020

KEYWORDS: Raman spectroscopy, Nanoprobes, In vivo imaging, Gold, Nanoparticles, Temporal resolution, Plasmonics, Target detection, Biosensing, Spatial resolution

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Proceedings Article | 21 February 2020 Presentation + Paper

Fiberoptics SERS sensors using plasmonic nanostar probes for detection of molecular biotargets

Vanessa Cupil-Garcia, Pietro Strobbia, Yang Ran, Bridget Crawford, Hsin-neng Wang, Rodolfo Zentella, Tai-Ping Sun, Tuan Vo-Dinh

Proceedings Volume 11257, 112570O (2020) https://doi.org/10.1117/12.2552993

KEYWORDS: Surface enhanced Raman spectroscopy, Sensors, Rhodamine B, Fiber optics sensors, Gold, Raman spectroscopy, Silver, Plasmonics, Signal detection, Fiber optics

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Proceedings Article | 9 September 2019 Paper

Inverse molecular sentinel-integrated fiber sensor for direct detection of miRNA targets

Pietro Strobbia, Yang Ran, Bridget Crawford, Vanessa Cupil-Garcia, Rodolfo Zentella, Hsin-Neng Wang, Tai-ping Sun, Tuan Vo-Dinh

Proceedings Volume 11082, 110822L (2019) https://doi.org/10.1117/12.2529844

KEYWORDS: Fiber optics sensors, Target detection, Sensors, Raman spectroscopy, Nanosensors, Optical fibers

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Proceedings Article | 9 September 2019 Presentation + Paper

In vivo detection of microRNA within plants using plasmonic nanosensors

Bridget Crawford, Pietro Strobbia, Hsin-Neng Wang, Rodolfo Zentella, Maxim Boyanov, Zhen-Ming Pei, Tai-Ping Sun, Kenneth Kemner, Tuan Vo-Dinh

Proceedings Volume 11082, 1108215 (2019) https://doi.org/10.1117/12.2529818

KEYWORDS: Nanoprobes, Raman spectroscopy, Nanoparticles, In vivo imaging, Plasmonics, Biosensing, Plasmonic sensors

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Proceedings Article | 10 May 2019 Presentation + Paper

Surface-enhanced spatially offset Raman spectroscopy (SESORS) for subsurface detection of nanostar probes

Ren Odion, Pietro Strobbia, Bridget Crawford, Tuan Vo-Dinh

Proceedings Volume 11007, 110070I (2019) https://doi.org/10.1117/12.2524847

KEYWORDS: Raman spectroscopy, Skull, Surface enhanced Raman spectroscopy, Nanoparticles, Bone, Tissue optics, Raman scattering, Signal detection, Scattering, Molecular spectroscopy

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Proceedings Article | 10 May 2019 Paper

In vivo nucleic acid detection and imaging within whole plants using plasmonic nanosensors

Bridget Crawford, Pietro Strobbia, Hsin-Neng Wang, Rodolfo Zentella, Maxim Boyanov, Ren Odion, Zhen-Ming Pei, Tai-Ping Sun, Kenneth Kemner, Tuan Vo-Dinh

Proceedings Volume 11007, 1100708 (2019) https://doi.org/10.1117/12.2524840

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Proceedings Article | 7 March 2019 Presentation + Paper

Application of plasmonic nanoprobes for SERS sensing and imaging of biotargets in plant systems

Pietro Strobbia, Bridget Crawford, Hsin-Neng Wang, Rodolfo Zentella, Maxim Boyanov, Zhen-Ming Pei, Tai-Ping Sun, Kenneth Kemner, Tuan Vo-Dinh

Proceedings Volume 10894, 108940C (2019) https://doi.org/10.1117/12.2512010

KEYWORDS: Nanoprobes, Raman spectroscopy, Imaging systems, In vivo imaging, Functional imaging, Plasmonics, Biofuels

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Proceedings Article | 7 March 2019 Paper

Implantable "smart tattoo" SERS nanosensors for in vivo detection of nucleic acid biotargets in a large animal model

Hsin-Neng Wang, Janna Register, Andrew Fales, Naveen Gandra, Pietro Strobbia, Eugenia Cho, Alina Boico, Gregory Palmer, Bruce Klitzman, Tuan Vo-Dinh

Proceedings Volume 10894, 108941J (2019) https://doi.org/10.1117/12.2514634

KEYWORDS: Nanosensors, Animal model studies, Sensors, Raman spectroscopy, Plasmonics

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Proceedings Article | 26 February 2019 Presentation + Paper

A nanophotonic-based assay for point-of-care medical diagnostics of malaria in low and middle income countries

Hoan Ngo, Pietro Strobbia, Priya Vohra, Elizabeth Freedman, Agampodi Swarnapali De Silva Indrasekara, Walter Lee, Steve Taylor, Tuan Vo-Dinh

Proceedings Volume 10869, 108690V (2019) https://doi.org/10.1117/12.2512012

KEYWORDS: Target detection, Point-of-care devices, Signal detection, Diagnostics, Blood, Medical diagnostics, Surface enhanced Raman spectroscopy

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Proceedings Article | 26 February 2019 Presentation + Paper

Direct detection of nanostar probes through a monkey skull using inverse surface-enhanced spatially offset Raman spectroscopy (SESORS)

Ren Odion, Pietro Strobbia, Bridget Crawford, Tuan Vo-Dinh

Proceedings Volume 10868, 108680B (2019) https://doi.org/10.1117/12.2512011

KEYWORDS: Skull, Surface enhanced Raman spectroscopy, Nanoparticles, Raman spectroscopy, Bone, Raman scattering, Tissue optics

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Proceedings Article | 12 February 2018 Paper

Surface-enhanced patially offset Raman spectroscopy (SESORS) for biomedical applications

Ren Odion, Pietro Strobbia, Tuan Vo-Dinh

Proceedings Volume 10484, 1048404 (2018) https://doi.org/10.1117/12.2300088

KEYWORDS: Raman spectroscopy, Surface enhanced Raman spectroscopy, Nanoparticles, Tissue optics, Signal detection, Gold, Raman scattering, Photons, Scattering, Particles

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SPIE Journal Paper | 19 July 2017

Nanomorphology and performance of pure and doped lead selenide for infrared detector

Narsingh Bahadur Singh, Christopher Cooper, Pietro Strobbia, Narasimha Prasad, Ching Hua Su, Bradley Arnold, Fow-Sen Choa

OE, Vol. 56, Issue 07, 077106, (July 2017) https://doi.org/10.1117/12.10.1117/1.OE.56.7.077106

KEYWORDS: Annealing, Lead, Cadmium, Infrared detectors, Glasses, Silicon, Nanorods, Mid-IR, Tin, Scanning electron microscopy

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Proceedings Article | 3 May 2017 Presentation + Paper

Plasmonic nanochip for SERS chemical and biomedical sensing

Hoan Ngo, Pietro Strobbia, Hsin-Neng Wang, Bridget Crawford, Andrew Fales, Tuan Vo-Dinh

Proceedings Volume 10215, 102150G (2017) https://doi.org/10.1117/12.2267759

KEYWORDS: Surface enhanced Raman spectroscopy, Plasmonics, Biosensing, Biosensors, Raman scattering, Target detection, Raman spectroscopy, Medical diagnostics, Signal detection, Genetics

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Proceedings Article | 3 May 2017 Presentation + Paper

Nanosensors for nucleic acid targets detection using SERS

Pietro Strobbia, Bridget Crawford, Hsin-Neng Wang, Tuan Vo-Dinh

Proceedings Volume 10215, 1021508 (2017) https://doi.org/10.1117/12.2267757

KEYWORDS: Surface enhanced Raman spectroscopy, Nanosensors, Target detection, Biosensors, Raman spectroscopy, Optical fibers, Nanoprobes, Gold, Microscopes, Biological research

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Proceedings Article | 13 May 2016 Paper

The development of Army relevant peptide-based surface enhanced Raman scattering (SERS) sensors for biological threat detection

Mikella Farrell, Pietro Strobbia, Deborah Sarkes, Dimitra Stratis-Cullum, Brian Cullum, Paul Pellegrino

Proceedings Volume 9863, 98630B (2016) https://doi.org/10.1117/12.2224102

KEYWORDS: Surface enhanced Raman spectroscopy, Biosensing, Metals, Raman spectroscopy, Sensors, Nanolithography, Fabrication, Scanning electron microscopy, Plasmons, Raman scattering

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SPIE Journal Paper | 20 October 2015 Open Access

Recent advances in plasmonic nanostructures for sensing: a review

Pietro Strobbia, Eric Languirand, Brian Cullum

OE, Vol. 54, Issue 10, 100902, (October 2015) https://doi.org/10.1117/12.10.1117/1.OE.54.10.100902

KEYWORDS: Plasmonics, Nanostructures, Surface enhanced Raman spectroscopy, Nanoparticles, Metals, Silver, Gold, Surface plasmons, Plasmons, Nanolithography

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Proceedings Article | 13 May 2015 Paper

Growth and morphology of lead tin selenide for MWIR detectors

Christopher Cooper, Pietro Strobbia, Emily Schultheis, Narasimha Prasad, Bradley Arnold, Fow-Sen Choa, Narsingh Singh

Proceedings Volume 9491, 949104 (2015) https://doi.org/10.1117/12.2179724

KEYWORDS: Lead, Tin, Glasses, Silicon, Sensors, Mid-IR, Long wavelength infrared, Annealing, Thin films, Infrared detectors

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Proceedings Article | 13 May 2015 Paper

Characterization of the role of oxide spacers in multilayer-enhanced SERS probes

Pietro Strobbia, Alex Henegar, Theodosia Gougousi, Brian Cullum

Proceedings Volume 9487, 94870P (2015) https://doi.org/10.1117/12.2177467

KEYWORDS: Surface enhanced Raman spectroscopy, Multilayers, Dielectrics, Atomic layer deposition, Oxides, Metals, Gold, Silver, Raman spectroscopy, Titanium dioxide

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Proceedings Article | 22 May 2014 Paper

Characterization of ultrathin oxide-based multilayer SERS nanoprobes for intracellular sensing

Pietro Strobbia, Brian Cullum

Proceedings Volume 9107, 910708 (2014) https://doi.org/10.1117/12.2049955

KEYWORDS: Surface enhanced Raman spectroscopy, Atomic layer deposition, Silver, Multilayers, Dielectrics, Surface plasmons, Oxides, Metals, Plasmons, Titanium dioxide

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Showing 5 of 22 publications

Conference Committee Involvement (3)

Smart Biomedical and Physiological Sensor Technology XXI

22 April 2024 | National Harbor, Maryland, United States

Smart Biomedical and Physiological Sensor Technology XX

1 May 2023 | Orlando, Florida, United States

Smart Biomedical and Physiological Sensor Technology XIX

4 April 2022 | Orlando, Florida, United States

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