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As human life expectancy increases, more people suffer from neurodegenerative diseases at the late stage of their lives. Currently, millions of people are affected and there is still no cure. Our team studied ways to transport retinoic acid, a substance to promote neuronal survival and growth as current methods do not reach the target neurons in the required amount. We present an innovative magnetic helical microrobot (MHM) to transport superparamagnetic iron oxide nanoparticles. The analysis provides us relations of the geometric parameters to obtain an optimum translational speed. Our magnetic applicator to control the MHM is based on a tri-axial Helmholtz electromagnetic coil system.
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Milenka Gamero, Jingfan Chen, Ya Wang, "Modeling drug delivery magnetic microrobots for neuron regeneration," Proc. SPIE PC12043, Active and Passive Smart Structures and Integrated Systems XVI, (18 April 2022); https://doi.org/10.1117/12.2615460