We aimed to integrate a series of novel optical techniques, termed coherent spatial imaging (CSI), into the same footprint as current pulse oximeters that provides absolute measurements of blood flow, oxygenation, oxy- and deoxy-hemoglobin concentrations, tissue scattering, and tissue absorption. We developed a first-generation, multi-wavelength CSI prototype for comparisons to diffuse optical spectroscopy and diffuse correlation spectroscopy (DOS/DCS). We measured silicone-base tissue phantoms and performed arterial occlusions to validate the CSI device. The CSI prototype results agreed with the DOS/DCS results. This is an important first step towards enhancing prolonged care through the development of a low-cost, multi-wavelength CSI device.
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