An IR Spectroscopic Characterization Of The Blood Component Platelet Activating Factor

E. C. Mushayakarara; H. H. Mantsch

doi:10.1117/12.970751

20 December 1985 An IR Spectroscopic Characterization Of The Blood Component Platelet Activating Factor

E. C. Mushayakarara, H. H. Mantsch

Proceedings Volume 0553, Fourier and Computerized Infrared Spectroscopy; (1985) https://doi.org/10.1117/12.970751
Event: 1985 International Conference on Fourier and Computerized Infrared Spectroscopy, 1985, Ottawa, Canada

Abstract

The platelet activating factor, PAF, has been recently identified as an ether lipid with dramatic bioreactivity. The present IR spectroscopic investigation demonstrates that in an aqueous environment PAF can assume three different structures, a micellar form at tempera-tures above 21°C, a solid-like opaque lamellar form at temperatures below 12°C, and an intermediate transparent lamellar form that exists at temperatures between 12 and 21Ã‚Â°C. The three structures are separated by two reversible phase transitions; however, the rate of the reversed micellar to lamellar change is negatively temperature dependent, i.e., about 6 min at -1°C and 12 min at 3°C, and slower than the lamellar to micellar change.

Citation Download Citation

E. C. Mushayakarara and H. H. Mantsch "An IR Spectroscopic Characterization Of The Blood Component Platelet Activating Factor", Proc. SPIE 0553, Fourier and Computerized Infrared Spectroscopy, (20 December 1985); https://doi.org/10.1117/12.970751

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