Miniature Laser Fluorescence Detector For Capillary Liquid Chromatography

Dennis C Shelly; Thomas J Edkins

doi:10.1117/12.945449

27 April 1988 Miniature Laser Fluorescence Detector For Capillary Liquid Chromatography

Dennis C Shelly, Thomas J Edkins

Proceedings Volume 0910, Fluorescence Detection II; (1988) https://doi.org/10.1117/12.945449
Event: 1988 Los Angeles Symposium: O-E/LASE '88, 1988, Los Angeles, CA, United States

Abstract

A miniature laser fluorescence system was developed as a low-cost, high-performance detector for capillary liquid chromatography. Using hybrid-microelectronic and optoelectronic devices to fabricate miniature electro/optic modules, a highly efficient measurement system was created. Detection limits for pyrene and perylene were determined to be about 500 fg and 10 fg, respectively, using less than 1 mW at 325 nm for pyrene and 13 MK at 442 nm for perylene. Significant improvements in performance will be achieved through more extensive use of the photon counting.

Citation Download Citation

Dennis C Shelly and Thomas J Edkins "Miniature Laser Fluorescence Detector For Capillary Liquid Chromatography", Proc. SPIE 0910, Fluorescence Detection II, (27 April 1988); https://doi.org/10.1117/12.945449

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