Recent progress in making protein microarray through BioLP

Rusong Yang; Lian Wei; Ying Feng; Xiujian Li; Quan Zhou

doi:10.1117/12.2266876

10 February 2017 Recent progress in making protein microarray through BioLP

Rusong Yang, Lian Wei, Ying Feng, Xiujian Li, Quan Zhou

Proceedings Volume 10250, International Conference on Optical and Photonics Engineering (icOPEN 2016); 102501U (2017) https://doi.org/10.1117/12.2266876
Event: Fourth International Conference on Optical and Photonics Engineering, 2016, Chengdu, China

Abstract

Biological laser printing (BioLP) is a promising biomaterial printing technique. It has the advantage of high resolution, high bioactivity, high printing frequency and small transported liquid amount. In this paper, a set of BioLP device is design and made, and protein microarrays are printed by this device. It’s found that both laser intensity and fluid layer thickness have an influence on the microarrays acquired. Besides, two kinds of the fluid layer coating methods are compared, and the results show that blade coating method is better than well-coating method in BioLP. A microarray of 0.76pL protein microarray and a “NUDT” patterned microarray are printed to testify the printing ability of BioLP.

Citation Download Citation

Rusong Yang, Lian Wei, Ying Feng, Xiujian Li, and Quan Zhou "Recent progress in making protein microarray through BioLP", Proc. SPIE 10250, International Conference on Optical and Photonics Engineering (icOPEN 2016), 102501U (10 February 2017); https://doi.org/10.1117/12.2266876

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