Assessing the spectrochemical signatures of skin components using FTIR microspectroscopy

Cassio A. Lima; Luciana Correa; Hugh J. Byrne; Denise M. Zezell

doi:10.1117/12.2527137

19 July 2019 Assessing the spectrochemical signatures of skin components using FTIR microspectroscopy

Cassio A. Lima, Luciana Correa, Hugh J. Byrne, Denise M. Zezell

Proceedings Volume 11073, Clinical and Preclinical Optical Diagnostics II; 110730S (2019) https://doi.org/10.1117/12.2527137
Event: European Conferences on Biomedical Optics, 2019, Munich, Germany

Abstract

Fourier Transform Infrared (FTIR) spectroscopy is a label-free analytical technique used to evaluate the chemical profile of a sample based on its molecular vibrations. The potential dermatological applications of FTIR spectroscopy has been well demonstrated over the past decades through many proof-of-concept studies evaluating cancerous and non-cancerous cutaneous diseases. Considering that the correctly identification of skin components plays an important role in the study of cutaneous diseases, the present study aims to evaluate the spectrochemical signatures of dermis and epidermis based on the pixels of a FTIR hyperspectral image collected from healthy skin.

Citation Download Citation

Cassio A. Lima, Luciana Correa, Hugh J. Byrne, and Denise M. Zezell "Assessing the spectrochemical signatures of skin components using FTIR microspectroscopy", Proc. SPIE 11073, Clinical and Preclinical Optical Diagnostics II, 110730S (19 July 2019); https://doi.org/10.1117/12.2527137

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