Optical methods for non-invasive assessment of arteriole flow impedance (Conference Presentation)

Jason Yang; Alexander Ruesch; Jana Kainerstorfer

doi:10.1117/12.2547639

9 March 2020 Optical methods for non-invasive assessment of arteriole flow impedance (Conference Presentation)

Jason Yang, Alexander Ruesch, Jana Kainerstorfer

Proceedings Volume 11226, Neural Imaging and Sensing 2020; 1122610 (2020) https://doi.org/10.1117/12.2547639
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

Vascular impedance is a frequency dependent quantity relating a vascular compartment's flow dynamics to pressure changes. Although vascular impedance has been investigated in larger arteries, probing smaller arterioles using similar techniques has been difficult due to their small cross-sectional area. Here we show how vascular impedance can be quantified based on pulsatile data from cerebral measurements using diffuse correlation spectroscopy (DCS) as well as near-infrared spectroscopy (NIRS). Results from head of bed tilting in healthy volunteers will be presented, showing that quantification of vascular impedance is possible. Applications and the relationship to cerebral autoregulation will be discussed.

Conference Presentation

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Jason Yang, Alexander Ruesch, and Jana Kainerstorfer "Optical methods for non-invasive assessment of arteriole flow impedance (Conference Presentation)", Proc. SPIE 11226, Neural Imaging and Sensing 2020, 1122610 (9 March 2020); https://doi.org/10.1117/12.2547639

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KEYWORDS

Head

Near infrared spectroscopy

Blood

Modulation

Blood circulation

Blood pressure

Cerebral blood flow

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