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The nervous system in the gastrointestinal wall is an autonomic nervous system that is essential for intestinal peristalsis, mucous secretion, and blood flow regulation. The degeneration or deficiency may cause passage disorder or functional obstruction. Pathological diagnosis accompanied by invasive tissue collection is essential for diagnosing the presence of this nervous system in the gastrointestinal wall. Therefore, we focused on Raman spectroscopy as a non-invasive diagnostic method. The purpose of this study is to develop new diagnostic methods based on optical techniques for non-invasive detection of the nervous system in the gastrointestinal wall using Raman spectroscopy.
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