Super-multiplexed vibrational imaging for complex biomedicine (Conference Presentation)

Wei Min

doi:10.1117/12.2543897

10 March 2020 Super-multiplexed vibrational imaging for complex biomedicine (Conference Presentation)

Wei Min

Proceedings Volume 11252, Advanced Chemical Microscopy for Life Science and Translational Medicine; 112520S (2020) https://doi.org/10.1117/12.2543897
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

The rapidly increasing need for systems biology stimulates the development of super-multiplexed methods for simultaneous imaging multiple biomolecules with distinct colors. The consensus is that complex biology requires multiplex technology. Fluorescent microscopy has inherent limitation due to the fundamental color barrier. In this end, vibrational imaging coupled with novel probes has the potential to address this grand challenge. Here we will present our recent advance along this direction including novel probe development, new labeling and amplification protocols, and application to tissue imaging. Exciting results on super-resolution super-multiplex imaging and high-dimensional single cell analysis will be discussed.

Conference Presentation

Citation Download Citation

Wei Min "Super-multiplexed vibrational imaging for complex biomedicine (Conference Presentation)", Proc. SPIE 11252, Advanced Chemical Microscopy for Life Science and Translational Medicine, 112520S (10 March 2020); https://doi.org/10.1117/12.2543897

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available