Stimulated Raman imaging with chemical probes for subcellular bioanalysis (Conference Presentation)

Lu Wei; Kun Miao; Jiajun Du

doi:10.1117/12.2546942

10 March 2020 Stimulated Raman imaging with chemical probes for subcellular bioanalysis (Conference Presentation)

Lu Wei, Kun Miao, Jiajun Du

Proceedings Volume 11252, Advanced Chemical Microscopy for Life Science and Translational Medicine; 112521S (2020) https://doi.org/10.1117/12.2546942
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

Innovations in optical spectroscopy and microscopy have revolutionized our understanding in biological systems at sub-cellular levels. In this talk, I will discuss about our recent development by coupling stimulated Raman scattering (SRS) microscopy with chemical probes that could allow new subcellular bioanalysis in live cells. The introduced tags offer additional SRS contrast channel for quantification of biological contents that were previously difficult. Both physical and chemical principles underlying the optical microscopy will be presented, as well as our efforts in biomedical applications including cancer- and neuronal- metabolism.

Conference Presentation

Citation Download Citation

Lu Wei, Kun Miao, and Jiajun Du "Stimulated Raman imaging with chemical probes for subcellular bioanalysis (Conference Presentation)", Proc. SPIE 11252, Advanced Chemical Microscopy for Life Science and Translational Medicine, 112521S (10 March 2020); https://doi.org/10.1117/12.2546942

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