Human brain meningioma tumor detection using visible resonance Raman spectroscopy

Liang Zhang; Yan Zhou; Shengjia Zhang; Binlin Wu; Ke Zhu; Cheng-hui Liu; Xinguang Yu; Robert R. Alfano

doi:10.1117/12.2577054

9 March 2021 Human brain meningioma tumor detection using visible resonance Raman spectroscopy

Liang Zhang, Yan Zhou, Shengjia Zhang, Binlin Wu, Ke Zhu, Cheng-hui Liu, Xinguang Yu, Robert R. Alfano

Proceedings Volume 11631, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIX; 1163104 (2021) https://doi.org/10.1117/12.2577054
Event: SPIE BiOS, 2021, Online Only

Abstract

Meningiomas are the most common brain neoplasms. They often show a wide distribution of locations and morphological attributes. Therefore, rendering tumor margin status is difficult during surgery. Accurate identification of tumor boundary intraoperatively is essential for total tumor removal and adjacent healthy tissue preservation. Visible resonance Raman (VRR) spectroscopy has been used for detection and diagnosis of human organ lesions since 2011. Here, we report for the first time the preliminary results on the evaluation of a VRR-LRRTM analyzer based on VRR technique to identify human brain meningioma grades and margins.

Citation Download Citation

Liang Zhang, Yan Zhou, Shengjia Zhang, Binlin Wu, Ke Zhu, Cheng-hui Liu, Xinguang Yu, and Robert R. Alfano "Human brain meningioma tumor detection using visible resonance Raman spectroscopy", Proc. SPIE 11631, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIX, 1163104 (9 March 2021); https://doi.org/10.1117/12.2577054

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