Seeing deep into engineered samples with dual-axis OCT

Adam P. Wax

doi:10.1117/12.2593463

21 June 2021 Seeing deep into engineered samples with dual-axis OCT

Adam P. Wax

Proceedings Volume 11786, Optical Methods for Inspection, Characterization, and Imaging of Biomaterials V; 1178603 (2021) https://doi.org/10.1117/12.2593463
Event: SPIE Optical Metrology, 2021, Online Only

Abstract

OCT adoption is somewhat limited by the lack of an effective means for obtaining adequate image penetration in highly scattering tissue. For example, the ability to observe subtle changes in the layers of skin tissue where microcirculation occurs, generally anywhere between 1-4 mm deep, a depth currently beyond the penetration of traditional OCT systems. DA-OCT presents an attractive potential to image deeper into tissues exposing morphology that otherwise may go undetected. The approach is based on an off-axis scanning approach which uses distinct illumination and collection apertures to accept a larger proportion of quasiballistic signal. Here we present transliation ofDA-OCT to image large tissue volumes using a broadband SLD centered about 1.3 μm paired with a dynamic focus-tracking method to create an enhanced depth of focus.

Conference Presentation

Citation Download Citation

Adam P. Wax "Seeing deep into engineered samples with dual-axis OCT", Proc. SPIE 11786, Optical Methods for Inspection, Characterization, and Imaging of Biomaterials V, 1178603 (21 June 2021); https://doi.org/10.1117/12.2593463

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