Cirrhosis of liver may cause structural distortion of entire liver by fibrosis and parenchymal nodules, in which the image findings in MR/CT images can be interpreted by shape, texture, volume, elasticity analysis and so on. To ease the workload of radiologists from interpretation of the numerous medical images, an online Computer-aided diagnosis (CAD) system on liver has been developing for quantifying the diagnosis of fibrosis. Several technologies regarding image processing and pattern recognition are introduced in this paper, including Shape, Texture, Volume, Elasticity Analysis and Edge computing with FPGA acceleration. The results by the novel methods on the non-invasive assessment of liver fibrosis as well as the role of our CAD scheme to replace traditional liver biopsy will be presented and discussed.
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