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The paper discusses the experimental stage of developing a device for the non-contact assessment of blood clotting using the method of laser-speckle correlation. The device based on this method will have a number of advantages over existing hemostasis analyzers: it allows the analysis of plasma micro samples, citrated and native blood by a non-contact optical method. The results of experiments with blood plasma, citrate and native blood, aimed at practical development of the method are presented and discussed. It has been shown that the method of laser-speckle correlation is promising for the creation of a new device for assessing blood clotting.
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Iullia D. Liushnevskaya, Fedor A. Gubarev, "Application of digital speckle patterns correlation for blood clotting time evaluation," Proc. SPIE 11845, Saratov Fall Meeting 2020: Optical and Nanotechnologies for Biology and Medicine, 1184509 (4 May 2021); https://doi.org/10.1117/12.2588460