Daria A. Varvina,1 Irina N. Dolganovahttps://orcid.org/0000-0002-7477-0572,2 Irina A. Shikunova,2 Anna I. Alekseeva,3 Pavel A. Karalkin,1 Kirill I. Zaytsev,4 Vladimir N. Kurlov2
1I.M. Sechenov First Moscow State Medical Univ. (Russian Federation) 2Institute of Solid State Physics (Russian Federation) 3Research Institute of Human Morphology (Russian Federation) 4A. M. Prokhorov General Physics Institute (Russian Federation)
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Multimodal sapphire scalpel for intraoperative diagnosis and therapy.
The multimodal sapphire scalpel was developed using the edge-defined film-fed growth technique aided by the cutting edge mechanical sharpening. The sapphire properties are combined with the presence of as-grown hollow internal capillary channels for the optical fibers accommodation. Thanks to the features of the sapphire scalpel, multimodal optical diagnosis of tissues with their dissection became available. The attained results justified a strong potential of the sapphire scalpel to become an efficient tool for minimizing the volume of the normal tissue removal around the tumor by detecting the tumor margins.
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Daria A. Varvina, Irina N. Dolganova, Irina A. Shikunova, Anna I. Alekseeva, Pavel A. Karalkin, Kirill I. Zaytsev, Vladimir N. Kurlov, "Multimodal sapphire scalpel for intraoperative diagnosis and therapy," Proc. SPIE 11949, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XX, 119490A (7 March 2022); https://doi.org/10.1117/12.2605965