Tessa G, George,1 Rebecca Rochowiak,2 Kelsey T. King,1 Daniel Lidstone,2 Carolina Pacheco,3 Sung Min Park,1 Dalin Yang,4 Mary Beth Nebel,2 Bahar Tunçgenç,5 Rene Vidal,3 Natasha Marrus,1 Stewart H. Mostofsky,2 Adam T. Eggebrechthttps://orcid.org/0000-0002-6320-26761
1Washington Univ. in St. Louis (United States) 2Kennedy Krieger Institute (United States) 3Johns Hopkins Univ. (United States) 4Washington University in St. Louis (United States) 5The Univ. of Nottingham (United Kingdom)
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There are gaps in our understanding of the neural signatures underlying naturalistic deficits associated with impaired motor imitation in autism spectrum disorder (ASD) due to logistical limitations in neuroimaging modalities like fMRI. Therefore, we utilized high-density diffuse optical tomography (HD-DOT) to image twenty-three young adults as they observed and imitated sequences of upper extremity movements. Alterations in multiple cortical areas were observed when comparing neural responses to motor observation and motor imitation in this sample. This establishes the utility of HD-DOT for neuroimaging during naturalistic overt motion
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Tessa G, George, Rebecca Rochowiak, Kelsey T. King, Daniel Lidstone, Carolina Pacheco, Sung Min Park, Dalin Yang, Mary Beth Nebel, Bahar Tunçgenç, Rene Vidal, Natasha Marrus, Stewart H. Mostofsky, Adam T. Eggebrecht, "Mapping cortical activity with high-density diffuse optical tomography (HD-DOT) during motor imitation," Proc. SPIE 12364, Clinical and Translational Neurophotonics 2023, 123640B (17 March 2023); https://doi.org/10.1117/12.2649096