Breast tumor margin delineation with high-resolution cone-beam x-ray computed tomography

Nattawut Sinsuebphon; Suphawat Laohawiriyakamol; Chalinee Thanasupsombat; Sorapong Aootaphao; Walita Narkbuakaew; Atthasak Kiang-ia; Tanapon Srivongsa; Puttisak Puttawibul; Pairash Thajchayapong; Saowapak Thongvigitmanee

doi:10.1117/12.2653797

10 April 2023 Breast tumor margin delineation with high-resolution cone-beam x-ray computed tomography

Nattawut Sinsuebphon, Suphawat Laohawiriyakamol, Chalinee Thanasupsombat, Sorapong Aootaphao, Walita Narkbuakaew, Atthasak Kiang-ia, Tanapon Srivongsa, Puttisak Puttawibul, Pairash Thajchayapong, Saowapak Thongvigitmanee

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Proceedings Volume 12468, Medical Imaging 2023: Biomedical Applications in Molecular, Structural, and Functional Imaging; 124681B (2023) https://doi.org/10.1117/12.2653797
Event: SPIE Medical Imaging, 2023, San Diego, California, United States

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Abstract

Breast-conserving surgery (BCS) is an alternative approach for tumor removal in breast tumor patients. This procedure requires confirmation of the tumor margin. In this study, a high-resolution cone-beam X-ray computed tomography (CBCT) was designed and evaluated for the application of breast tumor margin delineation. The imaging system was validated with a CBCT image quality phantom for spatial resolution and contrast. In addition, a breast phantom containing multiple pathological features was investigated. Finally, a breast tumor specimen was examined on the high-resolution CBCT. The results showed that the imaging system could provide a decent spatial resolution and great contrast. The pathological features of the breast phantom were clearly visible. The margin of the excised breast specimen was well defined by the system. Overall, the high-resolution CBCT provides a promising result for the clinical application.

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Nattawut Sinsuebphon, Suphawat Laohawiriyakamol, Chalinee Thanasupsombat, Sorapong Aootaphao, Walita Narkbuakaew, Atthasak Kiang-ia, Tanapon Srivongsa, Puttisak Puttawibul, Pairash Thajchayapong, and Saowapak Thongvigitmanee "Breast tumor margin delineation with high-resolution cone-beam x-ray computed tomography", Proc. SPIE 12468, Medical Imaging 2023: Biomedical Applications in Molecular, Structural, and Functional Imaging, 124681B (10 April 2023); https://doi.org/10.1117/12.2653797

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