CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume 12601 > Article
Open Access Paper
28 March 2023 Analysis of fluorescence collection efficiency for fiber optic scanning two-photon endomicroscopy
Conghao Wang, Huilan Liu, Aimin Wang, Lishuang Feng
Author Affiliations +
Proceedings Volume 12601, SPIE-CLP Conference on Advanced Photonics 2022; 1260107 (2023) https://doi.org/10.1117/12.2667161
Event: SPIE-CLP Conference on Advanced Photonics 2022, 2022, Online Only
Abstract
Piezoelectric ceramic tube fiber-scanning two-photon endomicroscopy is an essential division of miniature two-photon microscopy. The reverse collection optical path of the two-photon endomicroscopy platform is modeled and designed in this study. After simulating the chromatic aberration characteristics of the objective, the effects of the collection signal wavelengths, off-axis positions, fiber cladding diameters, and imaging depths on the collection efficiency are evaluated using Monte Carlo simulation. The results provide an additional theoretical explanation for enhancing the two-photon endomicroscopy platform's imaging sensitivity and signal-to-noise ratio.
© (2023) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Conghao Wang, Huilan Liu, Aimin Wang, and Lishuang Feng "Analysis of fluorescence collection efficiency for fiber optic scanning two-photon endomicroscopy", Proc. SPIE 12601, SPIE-CLP Conference on Advanced Photonics 2022, 1260107 (28 March 2023); https://doi.org/10.1117/12.2667161
PROCEEDINGS
 5 PAGES
DOWNLOAD PAPER SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
RIGHTS & PERMISSIONS
Get copyright permission  Get copyright permission on Copyright Marketplace
KEYWORDS
Fluorescence
Monte Carlo methods
Endomicroscopy
Cladding
Chromatic aberrations
Fluorescence intensity
Objectives
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top