Based on the method of cyclical body exercise correction optical coherent layer scan vascular angiography

Yule Xia; Qing He

doi:10.1117/12.2687535

28 August 2023 Based on the method of cyclical body exercise correction optical coherent layer scan vascular angiography

Yule Xia, Qing He

Author Affiliations +

Proceedings Volume 12724, Second International Conference on Biomedical and Intelligent Systems (IC-BIS 2023); 127242Q (2023) https://doi.org/10.1117/12.2687535
Event: Second International Conference on Biomedical and Intelligent Systems (IC-BIS2023), 2023, Xiamen, China

Abstract

Decorrelation-based OCTA is a widely used optical coherence tomography angiography method which utilizes OCT intensity information. However, cardiac and respiratory motions in animals seriously degrade image quality. This kind of bulk motion is periodic, and its C-Scan (slow scan) direction component hinders motion correction because of scan position and OCT structure’s change. Some correction methods were proposed, but vasculature information will be lost when larger bulk motion occur. Here we demonstrate a correction method which uses stitch scan protocol in C-Scan direction, and sets a threshold to the maximum value of normalized cross-correlation among repeated B-Scan intensity signal to exclude false OCT B-scans. Result of In vivo imaging experiment for mice indicates that our method can reserve whole vasculature information and effectively improve image quality.

Citation Download Citation

Yule Xia and Qing He "Based on the method of cyclical body exercise correction optical coherent layer scan vascular angiography", Proc. SPIE 12724, Second International Conference on Biomedical and Intelligent Systems (IC-BIS 2023), 127242Q (28 August 2023); https://doi.org/10.1117/12.2687535

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