The single-cell RNA sequencing technology and its application

Yichen Zhang

doi:10.1117/12.2692190

7 September 2023 The single-cell RNA sequencing technology and its application

Yichen Zhang

Proceedings Volume 12789, International Conference on Modern Medicine and Global Health (ICMMGH 2023); 127890H (2023) https://doi.org/10.1117/12.2692190
Event: International Conference on Modern Medicine and Global Health (ICMMGH 2023), 2023, Oxford, United Kingdom

Abstract

Single-cell RNA sequencing provides a methodology to analyse a specific type of cell’s gene expression under certain states simultaneously. It provides high resolution, high sensitivity and is able to detect rare cell types in order to achieve different experiment goals in clinical trials, at the same time illustrating the cell development trajectories, which allows scientists to reveal heterogeneity between different types of cells, and horizontally compare differences of genes in same cell type at its developmental stages. As a cutting-edge technology, single-cell RNA sequencing can be widely used in different types of experimental research, such as bioinformatics and molecular science, it has a promising future for development. This article introduced the development of Single-cell RNA sequencing, and it’s various approaches to encounter different purposes of using with specific types of collected sample, and discussed the applications in laboratory and why scientists prefer to use it.

Citation Download Citation

Yichen Zhang "The single-cell RNA sequencing technology and its application", Proc. SPIE 12789, International Conference on Modern Medicine and Global Health (ICMMGH 2023), 127890H (7 September 2023); https://doi.org/10.1117/12.2692190

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