Tissue temperature in an in-vivo porcine model during laser lithotripsy

Ron Marom; Julie J. Dau; Khurshid R. Ghani; Timothy L. Hall; William W. Roberts

doi:10.1117/12.3000635

15 March 2024 Tissue temperature in an in-vivo porcine model during laser lithotripsy

Ron Marom, Julie J. Dau, Khurshid R. Ghani, Timothy L. Hall, William W. Roberts

Proceedings Volume 12817, Advanced Photonics in Urology 2024; 128170I (2024) https://doi.org/10.1117/12.3000635
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

High fluid temperatures have occurred in studies with laser lithotripsy, yet temperature within the renal parenchyma has not been well characterized. Our objective was to measure renal tissue temperatures during laser activation in a calyx. Ureteroscopy was performed in porcine subjects with a prototype ureteroscope containing a temperature sensor at its tip. A needle with thermocouples was introduced percutaneously to allow temperature measurement in the renal medulla and cortex. Trials of 60 second laser activation (40 W) were conducted with irrigation of 8 ml/min. Substantial temperature elevation was observed in the renal medulla with thermal dose in two of nine trials exceeding threshold for tissue injury. In conclusion, high-power laser settings (40 W) can induce potentially injurious tissue temperatures in the in-vivo porcine model, particularly in the region adjacent to the collecting system.

Conference Presentation

Citation Download Citation

Ron Marom, Julie J. Dau, Khurshid R. Ghani, Timothy L. Hall, and William W. Roberts "Tissue temperature in an in-vivo porcine model during laser lithotripsy", Proc. SPIE 12817, Advanced Photonics in Urology 2024, 128170I (15 March 2024); https://doi.org/10.1117/12.3000635

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