A study on the role of radiomics feature stability in predicting breast cancer subtypes

Isabella Cama; Alejandro Guzman; Sara Garbarino; Cristina Campi; Karim Lekadir; Oliver Díaz

doi:10.1117/12.3027015

29 May 2024 A study on the role of radiomics feature stability in predicting breast cancer subtypes

Isabella Cama, Alejandro Guzman, Sara Garbarino, Cristina Campi, Karim Lekadir, Oliver Díaz

Proceedings Volume 13174, 17th International Workshop on Breast Imaging (IWBI 2024); 131741O (2024) https://doi.org/10.1117/12.3027015
Event: 17th International Workshop on Breast Imaging (IWBI 2024), 2024, Chicago, IL, United States

Abstract

Imaging features (radiomics) have potential for predicting Triple Negative Breast Cancer and other subtypes using magnetic resonance images (MRI). This work uses 244 images from the Duke-Breast-Cancer-MRI dataset to investigate the complex interplay between radiomics feature stability, with respect to segmentation variability, and prediction results of machine learning models. Our analysis reveals that features demonstrating high stability across different segmentations tend to enhance model performance, whereas unstable features sensitive to small segmentation changes degrade predictive accuracy. This exploration underscores the importance of feature stability in the development of reliable models for breast cancer subtype classification.

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Isabella Cama, Alejandro Guzman, Sara Garbarino, Cristina Campi, Karim Lekadir, and Oliver Díaz "A study on the role of radiomics feature stability in predicting breast cancer subtypes", Proc. SPIE 13174, 17th International Workshop on Breast Imaging (IWBI 2024), 131741O (29 May 2024); https://doi.org/10.1117/12.3027015

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