Monte Carlo simulations and measurements of signals in laser Doppler flowmetry on human skin

Marco H. Koelink; Frits F. M. de Mul; Jan Greve; Reindert Graaff; A. C. M. Dassel; Jan G. Aarnoudse

doi:10.1117/12.44178

1 May 1991 Monte Carlo simulations and measurements of signals in laser Doppler flowmetry on human skin

Marco H. Koelink, Frits F. M. de Mul, Jan Greve, Reindert Graaff, A. C. M. Dassel, Jan G. Aarnoudse

Proceedings Volume 1431, Time-Resolved Spectroscopy and Imaging of Tissues; (1991) https://doi.org/10.1117/12.44178
Event: Optics, Electro-Optics, and Laser Applications in Science and Engineering, 1991, Los Angeles, CA, United States

Abstract

Laser Doppler velocimetry provides a method for non invasive measurements of the perfusion of tissue. Therefore the tissue is illuminated with a monochromatic light source and back scattered light from the tissue is collected at a detector at an adjacent site. Some of the back scattered photons have had interaction with moving red blood cells and are frequency shifted. Due to interference of frequency shifted and non-frequency shifted photons the intensity at the detector fluctuates. These fluctuations provide the information from which a rate for the perfusion can be derived. In this paper we present perfusion measurements and Monte Carlo (MC) simulations on both a scale model and human skin tissue. The Monte Carlo results are used to quantify the size and position of the probe volume. Three different ways are presented to vary the size and position of the probe volume.

Citation Download Citation

Marco H. Koelink, Frits F. M. de Mul, Jan Greve, Reindert Graaff, A. C. M. Dassel, and Jan G. Aarnoudse "Monte Carlo simulations and measurements of signals in laser Doppler flowmetry on human skin", Proc. SPIE 1431, Time-Resolved Spectroscopy and Imaging of Tissues, (1 May 1991); https://doi.org/10.1117/12.44178

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