Detection of atherosclerosis via magnetic resonance imaging

Andrew L. Alexander; Victor T. Pytlewski; Michael F. Brown; Arthur F. Gmitro

doi:10.1117/12.137320

28 August 1992 Detection of atherosclerosis via magnetic resonance imaging

Andrew L. Alexander, Victor T. Pytlewski, Michael F. Brown, Arthur F. Gmitro

Proceedings Volume 1642, Diagnostic and Therapeutic Cardiovascular Interventions II; (1992) https://doi.org/10.1117/12.137320
Event: OE/LASE '92, 1992, Los Angeles, CA, United States

Abstract

Magnetic resonance imaging (MRI) of atherosclerotic lipids using a stimulated-echo diffusion- weighted (STED) sequence is demonstrated. The STED sequence exploits the large difference in diffusion between lipid (primarily cholesteryl ester) and water. The optimization of the STED sequence is discussed. The results of lipid imaging are corroborated with nuclear magnetic resonance (NMR) spectroscopy. This technique is non-invasive, and therefore, it is potentially useful in following the progression of the disease in animal models and in humans.

Citation Download Citation

Andrew L. Alexander, Victor T. Pytlewski, Michael F. Brown, and Arthur F. Gmitro "Detection of atherosclerosis via magnetic resonance imaging", Proc. SPIE 1642, Diagnostic and Therapeutic Cardiovascular Interventions II, (28 August 1992); https://doi.org/10.1117/12.137320

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